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Oberseminar SS 12: High-Throughput Methods in Life Science
High-throughput methods allow the simultaneous measurement of many cellular variables, such as protein content, gene expression or cell state. They have become an integrated part of current biological research to unravel the complexity of living systems and technology is advancing at a rapid pace. This seminar is aimed at presenting the latest methods in proteomics, genomics and deep sequencing, as well as strategies to turn this data into new discoveries in biology and treatments in medicine.
Dozenten:
Anmeldung und Themenwunsch per e-mail
Vorbesprechung: Dienstag 26. 4. 2012, 14:00 Uhr, Seminarraum ZBSA
Seminar: Donnerstag, den 5. 7. 2012, 14:00 Uhr, Seminarraum ZBSA
- 26. 04. 2012
- Vorbesprechung, Themenvorstellung
- Thema: Assessment of the Ubiquitin-Modified Proteome
- Vortragende: Deblina Patra
- Literatur: Kim et al., Molecular Cell 2011
- Betreuer: Jörn Dengjel
- Thema: Integrated Genomics- Proteomics-Metabolomics Picture of Cellular Metabolism
- Vortragende: Ariadna Pasqual
- Literatur: Sabido et al., MCP, 2012
- Literatur:Betreuer: Jörn Dengjel
- Thema: Selective Autophagy in Salmonella Growth
- Literatur: Wild et al., Science 2011
- Vortragender: Björn Schorch
- Betreuer: Jörn Dengjel
- Thema: NOISeq - detection of differential gene expression using RNA-seq data
- Literatur: Tarazona et al. Genome Res 2011 and Supplement
- Betreuer: Stefan Rensing
- Thema: Defintion of chromatin states in Arabidopsis thaliana using ChIP-seq
- Literatur: Roudier et al. EMBO J 2011
- Vortragender: Kai Gräber
- Betreuer: Stefan Rensing
- Thema: Detecting Novel Associations in Large Data Sets
- Literatur: Reshef et al., Science 2011 and Commentary to this article
- Vortragender: Dominik Mertens
- Betreuer: Arnd Brandenburg
- Thema: Core computational and statistical problems in the field of high-throughput proteomics
- Vortragende: Shalaka Wahane
- Literatur: Noble and MacCoss, Plos Comp. Biology, 2012
- Betreuer: Arnd Brandenburg
- Thema: Challenges and advances in RNA sequencing
- Literatur: Wang et al., Nat Rev Genet. 2009
- Betreuer: Arnd Brandenburg
- Thema: Boolean Modeling of the EGFR/ERbB Signaling
- Literatur: Samaga et al., Plos Comp Biol. 2009
- Betreuer: Hauke Busch
- Thema: Defining Gene Trajectories in differentiating cells
- Literatur: Mar and Quackenbusch, Plos Comp Biol. 2009
- Betreuer: Hauke Busch
- Thema: Dynamic interaction networks in a hierarchically organized tissue
- Literatur: Kirouac et al., Mol Syst Biol, 2010
- Betreuer: Hauke Busch
- Thema: Variations in DNA elucidate molecular networks that cause disease
- Literatur: Chen et al. Nature 2008
- Betreuer: Melanie Börries
- Thema: Variance of Gene Expression Identifies Altered Network Constraints in Neurological Disease
- Literatur: Mar and Quackenbush Plos Genetics, 2011
- Betreuer: Melanie Börries
- Thema: Genome-Wide Analysis of a Wnt1-Regulated Transcriptional Network Implicates Neurodegenerative Pathways
- Literatur: Wexler et al, Science Signaling, 2011
- Betreuer: Melanie Börries
